Sunifiram is a more advanced nootropic supplement, amongst those currently available. It was first researched around 2000, and although it has only been available for the public to buy, for the last few years, it has gained lots of attention and respect from nootropics researchers. Though still deemed to be "experimental", reviews have claimed a wide range of potent cognitive benefits, including enhanced memory, learning, alertness, attention and decision making. Beware...Sunifiram is a remarkably potent supplement, and believed to be around 1000 times the strength of Piracetam.
Sunifiram has a mechanism of action that stimulates many of the receptor groups found in other nootropics, but in different ways. This supplement works primarily on AMPA receptors and is known as an ampakine. AMPA receptors are associated with glutamate, which is an important neurotransmitter that is related to many facets of cognition. To understand how this is significant it is a good idea to gain some basic knowledge of how the brain works.